Safety desk
What needs a closer look before treatment?
Discuss pregnancy plans during the care visit.
For planned pregnancy, the label for semaglutide (Ozempic injection) says to stop ahead of time. [a]
As checked in September 2026, the Ozempic injection label sets a minimum gap of two months between stopping and a planned pregnancy. [a]
For tirzepatide (Zepbound), the label says to stop once pregnancy is known. [b]
Labels give different advice. Bring any plans for pregnancy and any questions about breastfeeding to the person who is caring for you.
Ask about the item you will actually receive.
Cold storage is right for some peptide medicines; others are kept at room temperature. [c]
Ask the pharmacist how to store the item on your label. Ask how to handle a delivery that fails to meet those storage needs.
The Food and Drug Administration (FDA), a U.S. agency, advises against using a weight-drug injection that arrives warm or lacks enough cold packing. [d]
Compounded means made to order.
A dose is the amount of medicine someone is meant to take. Ask the pharmacist to clear up any label or amount that is hard to understand.
The FDA has reports of dose mistakes with compounded semaglutide. Some people needed care in a hospital. [d]
When to get urgent help.
A severe allergic reaction can come on fast and may threaten life, according to MedlinePlus. [e]
Trouble swallowing, breathing, or a swollen face or tongue can be signs of that reaction. [e]
For severe signs, MedlinePlus says to call for emergency help or go to an emergency room. [e]
Taking more medicine than intended is called an overdose. MedlinePlus says to call poison control if there is an overdose. [c]
Reporting a medicine problem.
Patients can send medicine problem reports to the FDA through MedWatch, its reporting program. [f]
A report describes what happened. By itself, a report does not prove that the medicine caused the problem.
Keep the medicine’s label and the written care plan together. They can help you describe what happened when you contact the people involved.
Source notes
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Medicine label · Semaglutide injection
The pregnancy information for this specific product.
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Medicine label · Tirzepatide injection
A different pregnancy statement for a different product.
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MedlinePlus · Semaglutide information
How to store the medicine and get help after taking too much.
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FDA · Delivery and measurement concerns
Reports and concerns involving compounded weight medicines.
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MedlinePlus · Severe allergic reactions
Signs that need urgent medical help; a medical professional can assess the cause.
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FDA · MedWatch problem reporting
Patients and consumers can report medicine problems.